TB-500 is a synthetic fragment of thymosin beta-4 – a protein whose isolation dates back to the 1960s, while the TB-500 fragment itself has appeared in the literature since the 1990s. The PubMed database documents more than 200 independent publications dedicated to this molecule and its parent protein. TB-500 belongs to the group of small peptide fragments studied in the context of cytoskeletal biology.
In academic literature, TB-500 most commonly appears in connection with actin binding and its role in the structure of the cellular cytoskeleton. Scientific teams study it in in-vitro tissue models focusing on the dynamics of cellular proteins.
In the laboratory, it is used as a reference analytical standard – for HPLC calibration, mass spectrometry (LC-MS), and comparative binding experiments. Cerebrotech supplies it as a lyophilized powder in a glass vial with a Certificate of Analysis (COA), with HPLC-verified purity ≥ 98%. A mass spectrum is available upon request for each batch.
A compatible solvent for reconstitution – bacteriostatic water – is available separately in our catalog. The product is intended exclusively for laboratory in-vitro research, biochemical analysis, and academic purposes. It is not a medicine, food supplement, or cosmetic product. It is not intended for human or animal consumption, application to the body surface, ingestion, or inhalation. Sale is subject to age 18+ verification.