{"product_id":"g-l-p-3-10-mg","title":"GLP-3","description":"\u003cp data-start=\"0\" data-end=\"323\" class=\"PDq2pG_selectionAnchorContainer\"\u003eGLP-3 (LY3437943) is a reference synthetic peptide multidomain analog from the class of multi-receptor incretin agonists. In published literature, it is described as the first molecule of its kind to simultaneously activate three receptor systems: GIP receptor (GIPR), GLP-1 receptor (GLP-1R), and glucagon receptor (GCGR).\u003cspan aria-hidden=\"true\" class=\"PDq2pG_selectionAnchor\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 data-section-id=\"1wo6p3a\" data-start=\"325\" data-end=\"380\"\u003eInvestigated Biochemical Pathways (Academic Context)\u003c\/h2\u003e\n\u003cp data-start=\"382\" data-end=\"546\"\u003e\u003cstrong data-start=\"382\" data-end=\"410\"\u003eTriple Receptor Agonism:\u003c\/strong\u003e\u0026nbsp;in-vitro receptor binding assays on cloned GIPR\/GLP-1R\/GCGR receptors and characterization of signaling cascades (cAMP responses).\u003c\/p\u003e\n\u003cp data-start=\"548\" data-end=\"707\"\u003e\u003cstrong data-start=\"548\" data-end=\"580\"\u003eIncretin Metabolic Research:\u003c\/strong\u003e\u0026nbsp;academic interest in the research area of metabolic diseases (including diabetes mellitus and obesity as research areas).\u003c\/p\u003e\n\u003cp data-start=\"709\" data-end=\"927\"\u003e\u003cstrong data-start=\"709\" data-end=\"742\"\u003eModulation of AMPK signaling:\u003c\/strong\u003e\u0026nbsp;in-vitro models of glucose utilization and fatty acid oxidation at the level of isolated hepatocyte and adipocyte cultures (e.g., within the research area of fatty liver disease).\u003c\/p\u003e\n\u003cp data-start=\"929\" data-end=\"1085\"\u003e\u003cstrong data-start=\"929\" data-end=\"959\"\u003eExtended Pharmacokinetics:\u003c\/strong\u003e\u0026nbsp;binding interaction of the C20-acyl chain with albumin; subject of pharmacokinetic research at the in-vitro model level.\u003c\/p\u003e\n\u003ch2 data-section-id=\"1yg0v9z\" data-start=\"1087\" data-end=\"1116\"\u003eLaboratory Use and Storage\u003c\/h2\u003e\n\u003cp data-start=\"1118\" data-end=\"1518\"\u003eSuitable as a reference standard for HPLC, MS, and in-vitro receptor assays. In laboratory practice, lyophilized peptides are handled using appropriate sterile media. A compatible solvent intended exclusively for research purposes can be found in our offer as Bacteriostatic Water - 10 ml. To maintain the stability of the material's structure, cold storage and protection from light are recommended.\u003c\/p\u003e\n\u003ch2 data-section-id=\"toapjk\" data-start=\"1520\" data-end=\"1538\"\u003eProduct Purpose\u003c\/h2\u003e\n\u003cp data-start=\"1540\" data-end=\"1882\"\u003eThis material is sold exclusively as a reference standard for laboratory and in-vitro research, biochemical analysis, and educational purposes. It is not intended for human consumption, therapeutic use, application to the skin, ingestion, inhalation, or veterinary purposes. It is not a medicine, food supplement, cosmetic, or medical device.\u003c\/p\u003e\n\u003ch2 data-section-id=\"zyi10h\" data-start=\"1884\" data-end=\"1893\"\u003eAccess\u003c\/h2\u003e\n\u003cp data-start=\"1895\" data-end=\"2020\" data-is-last-node=\"\" data-is-only-node=\"\"\u003eSales are subject to confirmation of age 18+ and declaration of research or collector's purpose upon completion of the order.\u003c\/p\u003e","brand":"Cerebrotech","offers":[{"title":"10 mg","offer_id":54300886106441,"sku":null,"price":138.99,"currency_code":"EUR","in_stock":true},{"title":"20 mg","offer_id":54300886139209,"sku":null,"price":223.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0997\/6289\/7225\/files\/GLP-3.jpg?v=1782645311","url":"https:\/\/cerebrotech.eu\/en\/products\/g-l-p-3-10-mg","provider":"Cerebrotech","version":"1.0","type":"link"}